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. 2018 Dec 12;10:6869–6877. doi: 10.2147/CMAR.S186047

Table 1.

Distribution of clinicopathologic characteristics of the patients in the four categories, as classified by the number of examined LNs

Variable No. of examined nodes (n)
P-value
1–2 3–7 8–11 ≥12

Gender 0.744
 Male 21 (3.8%) 81 (14.8%) 80 (14.6%) 210 (38.3%)
 Female 7 (1.35%) 28 (5.1%) 30 (5.5%) 92 (16.8%)
Age (years) 0.022
 ≤65 13 (2.4%) 74 (13.5%) 84 (15.3%) 203 (37.0%)
 >65 15 (2.7%) 35 (6.4%) 26 (4.7%) 99 (18.0%)
Smoking status 0.956
 Never 11 (2.0%) 46 (8.4%) 43 (7.8%) 126 (23.0%)
 Former 17 (3.1%) 63 (11.5%) 67 (12.2%) 176 (32.1%)
Tumor size (cm) 0.984
 ≤4 21 (3.8%) 84 (15.3%) 86 (15.7%) 235 (42.8%)
 >4 7 (1.3%) 25 (4.6%) 24 (4.4%) 67 (12.2%)
Tumor location 0.002
 Left 12 (2.2%) 48 (8.7%) 62 (11.3%) 106 (19.3%)
 Right 16 (2.9%) 61 (11.1%) 48 (8.7%) 196 (35.7%)
Histological type 0.300
 Squamous 6 (1.1%) 30 (5.5%) 31 (5.6%) 107 (19.5%)
 Adenocarcinoma 19 (3.5%) 73 (13.3%) 66 (12.0%) 166 (30.2%)
 Adenosquamous 2 (0.4%) 5 (0.9%) 11 (2.0%) 20 (3.6%)
 Others 1 (0.2%) 1 (0.2%) 2 (0.4%) 8 (1.5%)
Visceral pleura invasion 0.108
 Yes 11 (2.0%) 67 (12.2%) 71 (12.9%) 184 (33.5%)
 No 17 (3.1%) 42 (7.7%) 39 (7.1%) 118 (21.5%)
Bronchia invasion 0.002
 Yes 3 (0.5%) 20 (3.6%) 22 (4.0%) 97 (17.7%)
 No 25 (4.6%) 89 (16.2%) 88 (16.0%) 205 (37.3%)
Surgical approach <0.001
 Thoracotomy 18 (3.3%) 99 (18.0%) 95 (17.3%) 273 (49.7%)
 VATS 10 (1.8%) 10 (1.8%) 15 (2.7%) 29 (5.3%)
Place of tumor relapse 0.271
 Intrathoracic metastases 2 (1.5%) 17 (12.7%) 14 (10.4%) 41 (30.6%)
 Systemic metastases 4 (3.0%) 11 (8.2%) 18 (13.4%) 27 (20.1%)

Abbreviations: LN, lymph node; VATS, video-assisted thoracoscopic surgery.