Table 1.
Treatment | Patient information |
Pretreatment cellularity |
Posttreatment cellularity |
Patient outcome |
---|---|---|---|---|
Hypofractionated radiation | 10 year old, male, Labrador | Tumor 68% Lymph/mono 12% PMN 2% Stroma 19% |
Tumor 55% Lymph/mono 15% PMN 4% Stroma 26% |
Euthanized due to local and metastatic cancer; 5 months post treatment |
Magnetic nanoparticle hyperthermia | 11 year old, male, Siberian Husky | Tumor 70% Lymph/mono 11% PMN 2% Stroma 17% |
Tumor 26% Lymph/mono 18% PMN 18% Stroma 38% |
Euthanized due to local and metastatic cancer; 26 months post treatment |
Hypofractionated radiation + virus like particles | 7 year old male Labrador | Tumor 74% Lymph/mono 16% PMN 1% Stroma 13% |
Tumor 18% Lymph/mono 21% PMN 13% Stroma 48% |
Tumor free when euthanized due to GI torsion; 5 months post treatment |
Hypofractionated radiation + virus like particles | 12 year old, female Beagle | Tumor 87% Lymph/mono 6% PMN 1% Stroma 13% |
Tumor 29% Lymph/mono 45% PMN 9% Stroma 17% |
Alive and tumor free; 20 months post treatment |
Hypofractionated radiation + virus like particles+ magnetic nanoparticle hyperthermia | 9 year old, male Rottweiler | Tumor 69% Lymph/mono 14% PMN 2% Stroma 25% |
Tumor 21% Lymph/mono 22% PMN 11% Stroma 46% |
Tumor free when euthanized due to non-cancer issue: 10 months post treatment |