Extended Data Table 2.

Antibiotics and probiotics

Top, 3,678 antibiotic prescriptions in the TEDDY microbiome study population by clinical centre. Bottom, early probiotic supplementation in TEDDY clinical centres. Probiotic use was stratified into three categories: probiotics during the first 4 weeks of life (early probiotic); probiotics before the first stool sample (roughly at three months) but not the first 4 weeks (later probiotic); and no probiotics before the first stool sample (no probiotic). Data for probiotics are presented as n (percentage).