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. Author manuscript; available in PMC: 2018 Dec 17.
Published in final edited form as: J Mol Med (Berl). 2017 Sep 4;95(11):1167–1178. doi: 10.1007/s00109-017-1587-4

Fig. 1.

Fig. 1

Tumor heterogeneity converges on recurrent cellular phenotypes. a Variations at the genomic, transcriptomic, epigenetic, and proteomic levels influence cellular phenotype b Tumor subclones vary widely in terms of mutational status, epigenetic changes, stochastic transcriptional and translational events, etc. c Changes converge on pathways that output recurrent phenotypes A and B