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Fallopian tube high-grade serous adenocarcinoma distending the tubal lumen (A). Residual plical structures are present (lower left). Corresponding endometrium shows microscopic papillary tumor fragments and focal replacement of the surface epithelium by serous adenocarcinoma (B). The tumors at both sites show aberrant/mutation-type p53 staining (C) and WT1 expression (D) (endometrial tumor depicted) favoring the interpretation of a primary tubal carcinoma with spread to the endometrium.
