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. 2017 Nov 17;43(1):12–25. doi: 10.1097/PAS.0000000000000991

FIGURE 3.

FIGURE 3

Histopathologic findings of UB-MNAC: adverse pathologic characteristics and metastasis. A, High mitotic activity. Blue circles indicate mitotic figures. B, Coagulative tumor cell necrosis. C, Sarcomatous component resembling nonspecific spindle cell sarcoma. D, Sarcomatous component showing severe nuclear pleomorphism. Note large, bizarre nuclei with intranuclear vacuoles (right upper and lower corners). E, Lymphovascular invasion. F, Histopathologic examination of pulmonary metastatic lesion reveals the carcinomatous component in the glandular pattern only.