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. Author manuscript; available in PMC: 2019 Dec 17.
Published in final edited form as: Analyst. 2018 Dec 17;144(1):206–211. doi: 10.1039/c8an01157e

Fig. 4.

Fig. 4

The 96-zone, paper-based Transwell assay format. The individual components of the device pictured in (a) include: (i) an acrylic top insert with a silicone gasket, (ii) a paper-based scaffold, (iii) a silicone gasket, and (iv) an acrylic bottom insert with a silicone gasket and bottom sheet of acrylic. (b) Top-view of the assembled device. (c) Side-view of the assembled device. (d) M231 cell invasion from collagen-containing paper scaffolds after a 48 h exposure to medium containing increasing concentrations of FBS. Each bar represents the average and standard error of the mean of n = 21 zones from a single setup. *p < 0.05, and ****p < 0.0001.