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. Author manuscript; available in PMC: 2020 Jan 1.
Published in final edited form as: Shock. 2019 Jan;51(1):10–22. doi: 10.1097/SHK.0000000000001243

Table 4.

Humane Modeling Endpoints Working Group (WG): Recommendations (R) and Considerations (C)

Humane Modeling (WG-2)

  • 1. The development and validation of standardized criteria to monitor the well-being of septic animals is recommended

  • 2. The development and validation of standardized criteria for euthanasia of septic animals is recommended (exceptions possible)

  • 3. Analgesics recommended for surgical sepsis should be consistent with ethical considerations

 R
  • a.

    Consider analgesics for nonsurgical sepsis

 C