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. 2018 Dec 17;50(12):166. doi: 10.1038/s12276-018-0192-0

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — a Micro-CT images of sections of the mouse distal femora and 3D reconstruction of the trabecular bone area. Bars: 300 μm (upper panels of each gender) and 100 μm (lower panels of each gender). GNX gonadectomy, MSCT mesenchymal stem cell transplantation in GNX mice. b–e Quantitative parameters of trabecular bone. BV/TV, bone volume over tissue volume; Tb.Th trabecular thickness, Tb.N trabecular number, Tb.Sp trabecular separation. n = 5 per group. The data represent the means ± SD. *P < 0.05; NS not significant (P > 0.05)