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. 2018 Dec 11;9:612. doi: 10.3389/fgene.2018.00612

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Copyright © 2018 Sollazzo, Genchi, Paglia, Di Giacomo, Pession, de Biase and Grifoni.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The majority of lgl^-/- cells forms multifocal nests which colonise a large fraction of the MYC-overexpressing tissue. (A–B1) Immunostaining for Lgl (red) and MYC (cyan) on wing discs from late w; l(2)gl⁴, FRT40A/Ubi-GFPnls, FRT40A; hh-Gal4/UAS-dm larvae. (C) Pie chart illustrating the numerical proportions of overgrown, mild and severe multifocal lgl^-/- clones found in the P compartment of w; l(2)gl⁴, FRT40A/Ubi-GFPnls, FRT40A; hh-Gal4/UAS-dm wing discs. The basic genotype is indicated on the left of the figure panel. P compartments are outlined in A1,B1, and disc axes are indicated in A,B. Magnification is 400×.