| Scoring methods for stromal tumor-infiltrating lymphocytes (sTILs) as recommended by the International TILs Working Group were feasible in clinical practice. | |
| Higher baseline sTILs in pre-NAC core needle biopsy were associated with higher pCR rate and better prognosis in HER2-positive breast cancers. | |
| A 20% threshold for sTILs may be feasible to predict pCR to NAC and prognosis in HER2-positive breast cancers. |
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