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Effect of 2.0 μg ml−1 shRNA delivered using (A) PLGA-shRNA-1 NP and (B) PLGA-shRNA-4 on the invasion of MDA-MB231 cells. Data are mean ± SD with n = 3. *P < 0.05, **P < 0.01, ***P < 0.001, where significance is determined by comparison with invasion following treatment with blank NP
