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. 2016 Oct;16(5):459–464. doi: 10.7861/clinmedicine.16-5-459

Table 1.

What patients need to know about their medicines

Knowledge Comment and examples
The reason for taking the medicine This will provide justification for adhering to the treatment regimen and enable the patient to explain the indications for therapy to other clinicians
How the medicine works Many patients will be interested in how a medicine works and this may provide additional justification and confidence in the prescribing decision
How to take the medicine This may be important for maximising effectiveness (eg metered-dose inhalers) and safety (eg bisphosphonate tablets)
What benefits to expect This will help to affirm the benefits of continued adherence to the medicine if it is working and allow more rapid reconsideration of the prescription if it is not
What adverse effects might occur
• common This may reduce anxiety and distress, especially if there are unpleasant but short-lived symptoms (eg nitrate-induced headache)
• serious This may influence the initial decision to accept treatment but also allows potentially serious adverse outcomes to be recognised at an early stage and avoided
Precautions that improve safety
• symptoms to report Those suggestive of emerging adverse effects might allow early discontinuation of therapy (eg sore throat related to bone marrow toxicity)
• monitoring required The importance of any monitoring regimen should be emphasised (eg measurement of renal function after prescription of nephrotoxic drugs, plasma drug levels of anti-epileptic drugs)
• potential drug-drug interactions The possibility of important drug interactions should be highlighted (eg warfarin)
• altered behaviour Some patients might need to alter behaviour when exposed to drugs (eg photosensitivity caused by amiodarone, abstinence from alcohol with metronidazole)
When to return for review The need to assess the impact of a prescription will often necessitate a review and patients should know when this will be