Table 5.
Results of T-test analysis for the real-time PCR validation of mRNA:miRNA pairs in the hippocampus of 2- and 9-month-old SAMP8 mice.
| T-test | ||||
|---|---|---|---|---|
| miRNA | N/group | t | P-value | |
| 2 months | Let-7e-5p | 4 | 5.048 | 0.002 |
| miR-26b-5p | 4 | 5.457 | 0.002 | |
| miR-29a-3p | 4 | 8.992 | <0.001 | |
| miR-146a-5p | 4 | 3.059 | 0.022 | |
| miR-181a-5p | 4 | 5.107 | 0.002 | |
| 9 months | Let-7c-5p | 4 | 7.032 | <0.001 |
| Let-7e-5p | 4 | 6.336 | <0.001 | |
| miR-128-3p | 4 | 4.784 | 0.003 | |
| miR-191 | 4 | 29.79 | <0.0001 | |
| mRNA | ||||
| 2 months | Hmg-20b | 4 | 10.95 | <0.001 |
| Nup160 | 4 | 2.842 | 0.047 | |
| Pou3f2 | 4 | 3.093 | 0.037 | |
| P2rx1 | 4 | 2.245 | 0.066 | |
| 9 months | Pbx1 | 4 | 2.976 | 0.025 |
| Socs6 | 4 | 4.737 | 0.003 | |