Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2018 Dec 11;9:1462. doi: 10.3389/fphar.2018.01462

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2018 Delpiano, Thomas, Yates, Rice, Gray and Saint-Criq.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Chronic esomeprazole does not disrupt epithelial integrity of CF hAECs. (A) Effect of increasing concentrations of apical esomeprazole on TransEpithelial Electrical Resistance (TEER) and Fluorescein Flux measured in Ussing chambers in the presence of a basolateral to apical Cl^- gradient (n = 5, five donors). (B,C) Effect of increasing concentrations of apical eso on resting short-circuit current (Isc, B, n = 5), and (C) amiloride-sensitive Isc (ΔIsc_(amil), black triangle, n = 5), Fsk-induced Isc (ΔIsc_(Fsk), open triangle, n = 5), CFTRinh172-sensitive Isc (ΔIsc₍₁₇₂₎, open diamond, n = 5) and UTP-induced Isc (ΔIsc_(UTP), black circles, n = 5).