Table 1. Demographic and clinical characteristics of 6,008 patients with community-acquired pneumonia in the study.
| Characteristic | Value |
|---|---|
| Age | |
| Median [interquartile range], years | 52 [7–75] |
| Sub group (years), n (%) | |
| 0–1 | 449 (7.5) |
| 2–4 | 748 (12.5) |
| 5–9 | 510 (8.5) |
| 10–17 | 218 (3.6) |
| 18–44 | 805 (13.4) |
| 45–64 | 1,085 (18.1) |
| 65–79 | 1,190 (19.8) |
| ≥80 | 1,003 (16.7) |
| Female sex, n (%) | 2,422 (40.3) |
| Smoke, n (%) | |
| Current smoker1 | 549 (9.1) |
| Non smoker | 4,601 (76.6) |
| Undocumented | 858 (14.3) |
| Underlying disease2, n (%) | |
| Any | 2,410 (40.1) |
| Chronic lung disease | 987 (16.4) |
| Cardiovascular disease | 1,081 (18.0) |
| Chronic renal disease | 679 (11.3) |
| Neurologic disorder | 417 (6.9) |
| Chronic liver disease | 81 (1.3) |
| Diabetes mellitus | 679 (11.3) |
| Immunosuppression | 112 (1.9) |
| Other system disease | 485 (8.1) |
| Undocumented | 978 (16.3) |
| Maximum body temperature (°C), n (%) | |
| <36 | 27 (0.4) |
| 36–37.2 | 932 (15.5) |
| 37.3–38 | 1,071 (17.8) |
| 38.1–39 | 2,419 (40.3) |
| ≥39.1 | 1,424 (23.7) |
| Undocumented | 135 (2.2) |
| Symptom, n (%) | |
| Cough | 5,425 (90.3) |
| Chest pain | 422 (7.0) |
| Dyspnea or tachypnea | 1,629 (27.1) |
| Moist rales | 2,549 (42.4) |
| Radiographic findings, n (%) | |
| Consolidation or infiltrate | 2,107 (35.1) |
| Pleural effusion | 447 (7.4) |
| Other3 | 3,454 (57.5) |
| Severity of pneumonia, n (%) | |
| NSCAP | 4,937 (82.2) |
| SCAP | 1,071 (17.8) |
| Hospital treatment, n (%) | |
| Intensive care unit admission | 695 (11.6) |
| Invasive mechanical ventilation | 617 (10.3) |
| Extracorporeal membrane oxygenation | 71 (1.2) |
| Oxygen therapy | 2,331 (38.8) |
| Death in hospital | 168 (2.8) |
| Patients with eligible SFLRT4 | 1,182 (19.7) |
| Age median [interquartile range], years | 59 [29–76] |
| Underlying disease, n (%) | 588 (49.7) |
| SCAP, n (%) | 252 (21.3) |
| Patients without eligible SFLRT | 4,826 (80.3) |
| Age Median [interquartile range], years | 49 [6–74] |
| Underlying disease, n (%) | 1,822 (37.8) |
| SCAP, n (%) | 819 (17.0) |
1, smoker was defined as a person who smoked at least once a day, and this condition lasted for more than 6 months. 2, any underlying medical condition included chronic lung diseases (asthma, reactive airway diseases, chronic obstructive pulmonary disease, or obstructive sleep apnea), chronic heart disease (i.e., congenital heart disease for children, coronary artery disease or congestive heart failure, but not hypertension), immunosuppression (either due to chronic condition or medication, cancer, or HIV infection with a CD4 cell count of >200 per cubic millimeter), diabetes mellitus, chronic kidney disease (with or without dialysis), chronic liver disease (hepatitis, cirrhosis, or hepatic failure), neurologic disorder (epilepsy, cerebral palsy, dementia, Parkinson’s disease, or history of stroke), and other system disease that affected less than 1% of patients. Categories were not mutually exclusive and therefore do not sum to 100%. 3, denote those cases who had radiographic diagnosis of CAP, but no detailed radiographic findings provided in their questionnaires. 4, SFLRT indicates specimen obtained from lower respiratory tract, including eligible sputum, bronchoalveolar-lavage, endotracheal aspirate. There are significant differences in age media (P<0.001), underlying disease rate (P<0.001) and SCAP percentage (P<0.001) between the group with eligible SFLRT and the group without eligible SFLRT. Notably, those cases with the missing values of underlying diseases were not included into calculation for underlying disease rates.