Table 3. Pathological stages, surgical characteristics and perioperative data of patients undergoing lung resection according to the presence or absence of postoperative pulmonary or cardiovascular complications.
| Characteristic | Pulmonary complications | Cardio-vascular complications | |||||
|---|---|---|---|---|---|---|---|
| Yes (n=50) | No (n=101) | P value | Yes (n=23) | No (n=128) | P value | ||
| TNM cancer stage | 0.189 | 0.142 | |||||
| Stage I | 22 (44.0) | 52 (51.5) | 7 (30.4) | 67 (52.3) | |||
| Stage II | 23 (46.0) | 32 (31.7) | 12 (52.2) | 43 (33.6) | |||
| Stage III & IV | 5 (10.0) | 17 (16.8) | 4 (17.4) | 18 (14.1) | |||
| Duration of surgery, min | 157.8±51.5 | 161.4±57.8 | 0.710 | 174.2±62.8 | 157.6±54.1 | 0.191 | |
| Lung Resection | 0.804 | <0.001 | |||||
| Wedge/segment | 10 (20.0) | 16 (15.8) | 2 (8.7) | 24 (18.8) | |||
| Lobectomy | 30 (60.0) | 65 (64.4) | 9 (39.1) | 86 (67.2) | |||
| Pneumonectomy | 10 (20.0) | 20 (19.8) | 12 (52.2) | 18 (14.1) | |||
| VATS | 9 (18.0) | 22 (21.8) | 0.588 | 2 (8.7) | 29 (22.7) | 0.166 | |
| Duration of anesthesia, min | 246.7±78.2 | 235.9±61.8 | 0.324 | 259.2±65.0 | 235.8±67.7 | 0.128 | |
| Ventilation, TLV | |||||||
| VT, mL/kg PBW | 8.3±1.8 | 8.1±1.9 | 0.580 | 8.4±1.7 | 8.1±1.9 | 0.490 | |
| PEEP, cmH2O | 5.3±1.0 | 5.1±1.0 | 0.466 | 5.0±1.0 | 5.2±1.0 | 0.461 | |
| PPlateau, cmH2O | 19.0±5.6 | 18.8±5.7 | 0.855 | 20.9±6.3 | 18.4±5.5 | 0.060 | |
| Ventilation, OLV | |||||||
| VT, mL/kg PBW | 6.3±1.8 | 6.3±1.5 | 0.968 | 6.4±1.5 | 6.3±1.4 | 0.818 | |
| PEEP, cmH2O | 5.5±1.2 | 5.3±1.0 | 0.441 | 5.3±0.7 | 5.4±1.1 | 0.743 | |
| PPlateau, cmH2O | 22.0±5.2 | 21.3±6.4 | 0.485 | 24.1±5.2 | 21.0±6.2 | 0.029 | |
| Duration, min | 111.3±47.8 | 107.0±50.7 | 0.634 | 125.6±50.1 | 105.2±49.2 | 0.070 | |
| Fluid management | |||||||
| Intraoperative Fluids, mL | 1,101.8±520.1 | 1,133.3±665.9 | 0.772 | 1,407.9±799.1 | 1,070.9±570.4 | 0.016 | |
| IV fluids on POD1, mL | 1,282.9±636.0 | 1,223.3±959.4 | 0.709 | 1,351.0±827.1 | 1,223.3±866.5 | 0.535 | |
| NE infusion intra-operative | 18 (36.0) | 23 (22.8) | 0.085 | 11 (47.8) | 30 (23.4) | 0.015 | |
| NE infusion on POD | 15 (30.0) | 11 (10.9) | 0.003 | 11 (47.8) | 15 (11.7) | <0.001 | |
| Patients transfused | 7 (14.0) | 4 (4.0) | 0.042 | 4 (17.4) | 7 (5.5) | 0.065 | |
| Laboratory values | |||||||
| Hematocrit, % | 35.1±5.6 | 35.7±5.2 | 0.544 | 34.6±5.0 | 35.7±5.4 | 0.352 | |
| Creatinine, mM/L | 83.7±56.3 | 76.4±26.7 | 0.316 | 87.1±43.7 | 77.2±37.9 | 0.286 | |
Data given as mean ± standard deviation or number (percentage). Student t tests or Chi-squared tests were used for statistical tests. VATS, video-assisted thoracic surgery; TLW, two lung ventilation; VT, tidal volume; PBW, predicted body weight; PEEP, positive end-expiratory pressure; OLV, one lung ventilation; POD1, first postoperative day; NE, norepinephrine.