Table 2. Patient Characteristics of the study population.
Characteristics | Intrathoracic recurrence (n=489) | Extrathoracic recurrence (n=363) | Total (n=2,486) |
---|---|---|---|
Age (years), median [IQR] | 62 [55−69] | 61 [53−68] | 61 [54−68] |
Sex, n (%) | |||
Male | 338 (69.1) | 238 (65.6) | 1,586 (63.8) |
Female | 151 (30.9) | 125 (34.4) | 900 (36.2) |
Grade, n (%) | |||
Well | 9 (1.9) | 4 (1.2) | 132 (5.5) |
Moderate | 243 (51.6) | 172 (49.7) | 1,288 (54.0) |
Poor | 219 (46.5) | 170 (49.1) | 967 (40.5) |
Tumor size (cm), median (IQR) | 4.0 (3.0−5.0) | 4.1 (3.0−5.0) | 3.0 (2.2−4.5) |
Primary site, n (%) | |||
Upper lobe | 242 (49.5) | 173 (47.7) | 1,246 (50.1) |
Middle lobe | 34 (7.0) | 23 (6.3) | 164 (6.6) |
Lower lobe | 146 (29.9) | 134 (36.9) | 827 (33.3) |
Main bronchus and trachea | 40 (8.2) | 25 (6.9) | 168 (6.8) |
Overlapping | 27 (5.5) | 8 (2.2) | 81 (3.3) |
Histology, n (%) | |||
Adenocarcinoma | 262 (53.6) | 236 (65.0) | 1,541 (62.0) |
Squamous cell carcinoma | 189 (38.7) | 93 (25.6) | 779 (31.3) |
Others | 38 (7.8) | 34 (9.4) | 166 (6.7) |
T stage, n (%) | |||
T1 | 75 (15.3) | 52 (14.3) | 582 (23.4) |
T2 | 311 (63.6) | 234 (64.5) | 1,482 (59.6) |
T3 | 67 (13.7) | 53 (14.6) | 291 (11.7) |
T4 | 36 (7.4) | 24 (6.6) | 131 (5.3) |
N stage, n (%) | |||
N0 | 263 (53.8) | 165 (45.5) | 1,771 (71.2) |
N1 | 98 (20.0) | 90 (24.8) | 360 (14.5) |
N2 | 128 (26.2) | 108 (29.8) | 355 (14.3) |
AJCC 8th stage, n (%) | |||
I | 171 (35.0) | 87 (24.0) | 1,298 (52.2) |
II | 132 (27.0) | 125 (34.4) | 626 (25.2) |
IIIA | 186 (38.0) | 151 (41.6) | 562 (22.6) |
Surgical type, n (%) | |||
Lobectomy/Bilobectomy | 459 (93.9) | 340 (93.7) | 2,344 (94.3) |
Sublobectomy | 10 (2.0) | 8 (2.2) | 65 (2.6) |
Pneumonectomy | 20 (4.1) | 15 (4.1) | 77 (3.1) |
Surgical method, n (%) | |||
VATS | 136 (27.8) | 91 (25.1) | 967 (38.9) |
Open | 350 (71.6) | 268 (73.8) | 1,481 (59.6) |
Hybrid VATS | 3 (0.6) | 4 (1.1) | 38 (1.5) |
IQR, interquartile range; VATS, video-assisted thoracoscopic surgery.