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. 2017 Feb;17(1):71–77. doi: 10.7861/clinmedicine.17-1-71

Table 3.

Disease modifying drugs (DMDs) used in Behçet’s disease

Oral DMDs Dose of drug
Azathioprine 2–3 mg/kg/day
Mycophenolate mofetil 2–3 gram/day
Methotrexate 20–25 mg/week
Tacrolimus 4–8 mg/day (depending on plasma trough levels)
Ciclosporin 2–5 mg/kg/day
Sulfasalazine 2–3 g/day
Dapsone 2–3 mg/kg/day
Thalidomide (exceptional use) 50–300 mg/day
Colchicine 0.5–2 mg/day
Prednisolone Variable dose (depending on indication and stage of treatment)
Parenteral treatment
Cyclophosphamide 15 mg/kg (vasculitis regimens)
Anti-TNF α inhibitors
Infliximab 5 mg/kg at 0, 2 and 6 weeks then onceevery 8 weeks
Adalimumab 40 mg every 2 weeks
Etanercept 50 mg/week
Certolizumab 400 mg at 0, 2 and 4 weeks then once every 4 weeks
Rituximab 1 g at 0 and 2 weeks
Interferon α Various regimens for Roferon A and pegylated interferon α 2b
Alemtuzumab 3 mg (day 1), 10 mg (day 3), 30 mg (day 5), 30 mg (day 8), 30 mg (day 10) and 30 mg (day 12)