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. 2018 Dec 11;12:61. doi: 10.3389/fnsys.2018.00061

FIGURE 5.

FIGURE 5

Response bias, reaction times and checking behavior as a function of target-lure similarity. (A) shows the mean response biases (Y-axis) for male and female Sham and PPT animals as a function of target-lure similarity (X-axis). The response bias was higher for more similar target-lure problems (F[3,78] = 40.26, p = 0.0001). The main effect on target-lure similarity on response bias did not interact with sex (F[3,78] = 1.24, p = 0.301). There was, however, a significant interaction with experimental group (F[3,78] = 3.40, p = 0.022), due to the PPT rats having larger response biases relative to the Sham animals as the target-lure similarity increased. (B) Shows the reaction times (Y-axis) as a function of target-lure similarity (X-axis). Reaction times were faster for the more similar lure conditions (F[3,78] = 6.99, p = 0.001). The tendency for rats to choose an object faster when the target and lure were more similar did not significantly interact with sex (F[3,78] = 0.68, p = 0.57), or group (F[3,78] = 1.92, p = 0.13). (C) Shows a schematic of checking behavior. (D) Shows the mean ratio of checking behavior to total trials (Y-axis) as a function of lure similarity (X-axis) for the different groups. Checking behavior significantly decreased as a function of target-lure overlap (F[3,78] = 33.79, p = 0.0001). The amount of checking behavior as a function of target-lure overlap did not significantly interact with sex (F[3,78] = 0.18, p = 0.91), or group (F[3,78] = 1.78, p = 0.16). However, there was a trend for the PPT rats to display significantly less checking behavior compared to sham animals (F[1,26] = 3.96, p = 0.057). ∗Indicates significant effect.