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. 2018 Nov 20;19(1):400–406. doi: 10.3892/mmr.2018.9671

Figure 3.

Figure 3.

Effects of pio and IL-6 on the expression of visfatin in BeWo cells. BeWo cells were treated with IL-6 (5 ng/ml) and/or pio (10 µM) for 48 h. (A and B) Pio significantly upregulated the expression levels of visfatin, which abrogated the inhibitory effects of IL-6 on visfatin in BeWo cells. *P<0.05 vs. IL-6; #P<0.05 vs. CON; †P<0.05 vs. CON, IL-6 and IL-6 + pio. (C) Treatment with pio significantly increased the secretion levels of visfatin in BeWo cell compared with IL-6 alone or in combination with pio. *P<0.05 vs. IL-6; #P<0.05 vs. IL-6 + pio. Data were presented as the mean ± standard deviation. CON, control; IL-6, interleukin 6; pio, pioglitazone.