Figure 5.
miR-210 promotes apoptosis of GC-2 cell by targeting KLF7. GC-2 cells were transfected with pcDNA3.1, miR-210 mimics, KLF7 mimics and miR-210 mimics + KLF7 mimics following hypoxic for 48 h. (A) Analysis of apoptotic cells. (B) Analysis of miR-210 expression. (C) Analysis of apoptosis-associated protein expression. *P<0.05, **P<0.01 vs. respective pcDNA3.1; #P<0.05, ##P<0.01 vs. miR-210. miR, microRNA; KLF7, Kruppel-like factor 7; PI, propidium iodide; Bax, apoptosis regulator BAX; Bcl-2, B-cell lymphoma 2; GC-2, GC-2spd.