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. 2018 Nov 21;19(1):205–212. doi: 10.3892/mmr.2018.9682

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Copyright: © Li et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 4. — DUSP1 expression level is associated with miR-133a-3p. (A) miR-133a-3p sequence demonstrates complementary binding to the sequence of the 3′UTR of DUSP1. (B) DUSP1 wild-type 3′UTR is associated with miR-133a-3p as observed in the luciferase reporter assay. (C) DUSP1 expression level is positively regulated by miR-133a-3p. (D) Protein expression level of DUSP1 is regulated by miR-133a-3p. **P<0.01 vs. NC. NC, negative control; miR, microRNA; DUSP1, dual specificity phosphatase 1; UTR, untranslated region.