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. 2018 Nov 21;19(1):205–212. doi: 10.3892/mmr.2018.9682

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Copyright: © Li et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 5. — Puerarin promotes the expression of DUSP1 in breast cancer cells. (A) Various concentrations of puerarin increase the DUSP1 protein expression level. (B) Puerarin regulates the expression levels of proteins downstream of DUSP1 by affecting the protein expression level of DUSP1. (C) Puerarin and miR-133a-3p inhibitor regulate the DUSP1 mRNA expression level. (D) Densitometric analysis. *P<0.05, **P<0.01 vs. respective NC. NC, negative control; DUSP1, dual specificity phosphatase 1; p-, phosphorylated; miR, microRNA.