Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2018 Nov 21;19(1):508–514. doi: 10.3892/mmr.2018.9680

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright: © Chen et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

PMC Copyright notice

Figure 5. — Restoration of ZIC2 reverses the effect of miRNA-1271-5p overexpression on AML cell proliferation and apoptosis. (A) Relative expression of ZIC2 in AML cells transfected with oeZIC2 was measured by reverse transcription-quantitative polymerase chain reaction. (B and C) Cell proliferation was determined by Cell Counting kit-8 assay in AML cells transfected with oeZIC2. (D) Cell apoptosis was analyzed by flow cytometry in AML cells transfected with indicated plasmids. Data are representative of three independent experiments and expressed as the mean ± standard deviation. *P<0.05 vs. the NC or miR-mimic group. AML, acute myeloid leukemia; miR, microRNA; NC, negative control; oeZIC2, Zic family member 2 overexpression plasmid.