Table I.

Top five biological functions and top ten KEGG pathways of the overlapped differentially expressed genes.

A, Biological process
ID	GO term description	Count	FDR
GO:0007166	Cell surface receptor signaling pathway	38	1.10×10-13
GO:0051239	Regulation of multicellular organismal process	40	1.10×10-13
GO:0030155	Regulation of cell adhesion	23	1.23×10-13
GO:2000026	Regulation of multicellular organismal development	32	1.41×10-12
GO:0070887	Cellular response to chemical stimulus	37	6.78×10-12
B, Molecular function
ID	GO term description	Count	FDR
GO:0005515	Protein binding	51	3.83×10-11
GO:0005102	Receptor binding	25	1.05×10-09
GO:0005003	Ephrin receptor activity	6	4.91×10-08
GO:0008201	Heparin binding	10	5.03×10-07
GO:0042802	Identical protein binding	20	5.17×10-07
C, Cellular component
ID	GO term description	Count	FDR
GO:0005615	Extracellular space	28	4.35×10-11
GO:0009986	Cell surface	19	2.35×10-08
GO:0005576	Extracellular region	42	8.80×10-07
GO:0009897	External side of plasma membrane	11	8.80×10-07
GO:0098552	Side of membrane	13	2.42×10-06
D, KEGG pathway
ID	GO term description	Count	FDR
4,060	Cytokine-cytokine receptor interaction	16	3.66×10-12
4,360	Axon guidance	9	3.42×10-07
4,062	Chemokine signaling pathway	10	3.69×10-07
5,340	Primary immunodeficiency	6	4.88×10-07
4,151	PI3K/AKT signaling pathway	10	8.41×10-05
4,630	JAK-STAT signaling pathway	7	1.87×10-04
5,162	Measles	6	7.14×10-04
4,640	Hematopoietic cell lineage	5	1.05×10-03
4,064	NF-κB signaling pathway	5	1.11×10-03
4,660	T cell receptor signaling pathway	5	1.52×10-03
5,142	American trypanosomiasis	5	1.52×10-03

ID, identification; FDR, False Discovery Rate; GO, Gene Ontology; KEGG, Kyoto Encyclopedia Genes and Genomes; NF-κB, nuclear factor-κB; JAK, Janus kinase; STAT, signal transducer and activator of transcription; AKT, protein kinase B; PI3K, phosphatidylinositol-4,5-bisphosphate 3-kinase.