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. 2018 Dec 11;9:1445. doi: 10.3389/fphar.2018.01445

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Copyright © 2018 Bao, Zheng, Tong, Zhu, Zhuang, Zheng and Wang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The forest plot: (A) in vivo effects of danshensu for increasing p-PI3K compared with controls (n = 10 per group); (B) in vivo effects of danshensu for increasing p-AKT compared with controls (n = 9 per group); (C) in vivo effects of danshensu for increasing Nrf2 compared with controls (n = 21per group); (D) in vivo effects of danshensu for increasing HO-1compared with controls (n = 10 per group); (E) in vivo effects of danshensu for increasing GST compared with controls (n = 16 per group); (F) in vivo effects of danshensu for increasing GSH-Pxcompared with controls (n = 12 per group). p-PI3K, phosphatidylinositol 3-kinase; p-AKT, phosphothreonine kinase; Nrf2, nuclear factor erythroid 2-related factor 2; HO-1, heme oxygenase-1; GST, glutathione-S-transferase; GSH-Px, glutathione peroxidase.