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Endothelial function in patients with cystic fibrosis before and after 4 wk of sildenafil treatment
| Variable | Baseline | 4-wk Sildenafil | P Value |
|---|---|---|---|
| Diameter, mm | |||
| Baseline | 3.00 (0.59) | 3.06 (0.60) | 0.294 |
| Peak | 3.22 (0.60) | 3.30 (0.60) | 0.035* |
| Absolute change | 0.21 (0.12) | 0.27 (0.09) | 0.012* |
| Shear rate, s−1, area under the curve | 50,656 (21,929) | 49,227 (18,866) | 0.796 |
| Time to peak, s | 49 (21) | 45 (16) | 0.646 |
Values are means (SD).
Statistically significant.
