Table 4.

Reproducibility of endothelial function assessments in patients with cystic fibrosis

			Between-Day Pre Visit 1 vs. Pre Visit 2
Variable	Pre Visit 1	Pre Visit 2	t-test	CV	CV′	ICC	r	BA plot
Diameter, mm
Baseline	3.07 (0.53)	3.04 (0.64)	0.558*	19.9*	0.01*	0.997, P < 0.01*	0.979, P < 0.01*	X*
Peak	3.32 (0.61)	3.21 (0.63)	0.576*	18.7*	0.02*	0.985, P < 0.01*	0.970, P < 0.01*	X*
FMD, %	7.6 (4.1)	7.5 (4.3)	0.615*	52.0	2.07*	0.940, P < 0.01*	0.982, P < 0.01*	X*
FMD (%)/shear (s-1, AUC)	0.16 (0.06)	0.15 (0.07)	0.507*	39.2	0.05*	0.854, P < 0.01*	0.825, P < 0.01*	X*

Values are means (SD). Reproducibility was evaluated using t-test statistic (P value), coefficient of variation (CV = SD/mean × 100), CV′ [CV′ = (100 × SD)/(mean + 100)], intraclass correlation coefficient (ICC), Pearson’s correlation coefficient (r), and Bland-Altman (BA) plot. X in the BA cell indicates an acceptable plot. FMD, flow mediated dilation.

^*Acceptable reproducibility.