Table 2.
Normal weight (n = 13) |
Overweight (n = 10) |
Obesity (n = 10) |
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Baseline | After | p | Baseline | After | p | Baseline | After | p | |
BMI (kg/m2) l,l l | 22.34±1.45 | 22.27±1.55 | NS | 27.25±1.47 | 27.15±1.39 | NS | 33.67±3.01 | 33.03±2.79 | <0.05 |
Waist (cm) l,l l | 78.05±6.45 | 77.96±6.29 | NS | 91.19±8.20 | 89.34±7.02 | NS | 106.55±8.45 | 104.04±7.85 | <0.01 |
Hip (cm) l,l l | 91.00±8.84 | 90.43±8.80 | NS | 102.35±4.95 | 102.11±4.63 | NS | 113.65±8.68 | 111.93±8.54 | NS |
Glucose (mg/dL)l,l l | 87.92±8.07 | 81.23±9.68 | <0.05 | 98.20±9.10 | 88.30±7.33 | <0.01 | 91.90±6.72 | 92.60±5.69 | NS |
Triglycerides (mg/dL) l l | 118.00±55.21 | 86.30±28.85 | <0.01 | 210.80±180.60 | 162.20±100.39 | 0.055 | 182.70±96.07 | 152.30±61.53 | NS |
Cholesterol (mg/dL) l, l l | 180.76±36.33 | 166.69±34.85 | <0.05 | 222.00±45.36 | 211.50±49.71 | NS | 182.30±38.85 | 176.60±25.39 | NS |
HDL-C (mg/dL)l, l l | 48.15±7.62 | 46.77±9.93 | NS | 48.80±14.79 | 47.50±8.48 | NS | 37.50±5.01 | 35.80±12.03 | NS |
LDL (mg/dL) | 108.99±26.39 | 102.66±25.56 | 0.093 | 131.04±15.70 | 131.56±39.49 | NS | 108.26±39.73 | 107.14±25.87 | NS |
Insulin (μU/L)l, l l | 6.40±2.47 | 4.69±2.32 | <0.001 | 12.40±11.46 | 8.60±8.47 | <0.05 | 13.15±6.00 | 16.16±6.26 | NS |
HOMA-IR l, l l | 1.41±0.66 | 0.95±0.53 | <0.001 | 3.15±3.28 | 1.91±1.92 | <0.01 | 3.00±1.46 | 3.73±1.55 | NS |
Irisin (ng/mL) | 9.38±1.60 | 9.71±1.76 | NS | 9.60±1.25 | 10.15±1.24 | <0.05 | 9.00±1.88 | 9.39±1.52 | NS |
Acute Irisin (ng/mL) | 9.92±1.52 | 11.50±2.03 | <0.05 | 9.43±1.35 | 10.70±1.57 | <0.05 | 9.26±1.31 | 10.87±1.79 | <0.01 |
Leptin (ng/mL) l, l l | 14.80±5.66 | 14.47±5.29 | NS | 23.00±10.17 | 17.87±8.02 | 0.074 | 28.67±14.08 | 26.30±13.21 | NS |
Adiponectin (μg/mL) l, l l | 9.36±3.95 | 7.26±2.93 | <0.05 | 7.07±3.31 | 6.31±2.76 | NS | 4.86±2.64 | 4.21±2.37 | <0.05 |
IL-6 (pg/mL) l, l l | 4.08±1.09 | 3.89±1.00 | NS | 4.01±0.56 | 3.57±0.67 | <0.05 | 6.69±5.68 | 6.80±5.10 | NS |
Acute IL-6 (pg/mL) | 3.98±1.24 | 5.49±2.63 | <0.05 | 3.91±0.65 | 4.74±1.16 | 0.061 | 7.87±7.33 | 8.33±5.02 | NS |
Apelin (n/mL) (n = 19) (Nw = 7 Ow = 6, Ob = 6) | 280.84±129.86 | 150.68±91.51 | <0.05 | 301.17±113.53 | 174.69±155.58 | NS | 209.29±110.66 | 187.00±144.53 | NS |
FGF-21 (pg/mL) | 445.48±238.35 | 417.48±147.60 | NS | 459.40±247.01 | 479.10±215.52 | NS | 633.76±422.09 | 662.67±340.67 | NS |
Acute FGF-21 (pg/mL) (n = 23) (Nw = 10 Ow = 7, Ob = 6) | 371.22±174.85 | 380.89±183.92 | NS | 511.79±270.41 | 558.53±305.52 | NS | 409.82±139.54 | 531.78±339.86 | NS |
Data are presented as mean standard deviation. Difference between BMI groups l before, l l after p < 0.05. NS, not significant. Waist adjusted by BMI.