Table 2.

Regions of significant volume changes between patients and controls.

Comparisons	Statistical values			Coordinates anatomical location
	Cluster size	t-value	p-value	x	y	z	Region
Control>Patient	4318	5.78	0.000	−1	−15	9	L Thalamus
		5.40	0.000	8	−9	6	R Thalamus
		5.01	0.000	−11	−10	15	L Thalamus
		4.11	0.000	−16	−36	8	L Hippocampus
	183	4.05	0.000	−29	−7	4	L Putamen
		3.47	0.001	−34	−8	7	L Insula*
	19	3.51	0.001	30	−13	−20	R Hippocampus*
	157	3.97	0.000	−5	24	−26	L Rectus
	170	3.79	0.000	56	−9	−12	R Sup temporal gyrus
	44	3.76	0.000	−45	−10	−12	L Sup temporal gyrus
		3.64	0.000	−38	−12	−5	L Insula
Patient>Control	no

The MNI coordinates and t-values for the local maxima of the centers of the voxel clusters. R, right hemisphere; L, left hemisphere; Sup, superior. Threshold for significant clusters reported here was set at p < 0.05, FDR correction, cluster size of 15.

^*Indicated the cluster is significant at p < 0.001, uncorrected, cluster size > 15.