. Author manuscript; available in PMC: 2018 Dec 18.

Published in final edited form as: Endocrine. 2017 Apr 12;56(3):495–503. doi: 10.1007/s12020-017-1300-y

Table 2.

Diagnostic accuracy of biochemical tests in the diagnosis of P/PGL

	Studies	SE	SP	AUC	TA	NPV		PPV
	[number]	[%]	[%]	[partial]^a	[%]	[0.5%]^b	[5%]^c	[0.5%]^b	[5%]^c

HPLC	15	94	93	0.947	93–94	n.a.		n.a.
IA	11	91	93	0.911	91–93	n.a.		n.a.
Supine	10	95^*	95^**	0.942	95–95	0.9997	0.9972	0.0872	0.5000
Seated	10	89^*	94	0.913	89–94	0.9994	0.9939	0.0694	0.4384
Urine	11	93	90^**	0.932	90–93	0.9996	0.9959	0.0446	0.3286

SE sensitivity; SP specificity; TA test accuracy range (for prevalence ranges between 0.0–1.0); NPV negative predictive value; PPV positive predictive value; n.a. not assessed

supine versus seated p<0.02;

^**

supine versus 24-h urine p<0.03

for details see Methods

prevalence of P/PGL among hypertensive subjects (0.2–0.6%)

prevalence of P/PGL in subjects with incidentaloma