Table 2.

CD-associated relative risks for lymphoma and gastrointestinal carcinoma: Stratified analysis by gender and age at CD diagnosis.

	T-cell lymphoma	Small bowel adenocarcinomaa	Esophageal SCC	Colorectal carcinoma
	RR (95% CI)	RR (95% CI)	RR (95% CI)	RR (95% CI)
No CD	1.0 (reference)	1.0 (reference)	1.0 (reference)	1.0 (reference)
CD	35.8 (27.1–47.4)	11.9 (8.2–17.2)	3.5 (2.1–5.8)	1.1 (0.9–1.4)
Gender
Male	35.9 (24.1–53.4)	12.4 (7.1–21.7)	1.2 (0.4–3.9)	1.1 (0.8–1.5)
Female	35.7 (24.1–53.0)	11.4 (6.9–18.9)	5.9 (3.3–10.3)	1.2 (0.9–1.6)
p heterogeneity	NS	NS	0.02	NS
Age at CD diagnosis
<60 years	27.4 (18.1–41.5)	8.1 (4.0–16.6)	1.7 (0.5–5.2)	1.0 (0.7–1.5)
≥60 years	46.1 (31.7–67.0)	14.2 (9.2–22.1)	4.7 (2.6–8.2)	1.2 (0.9–1.6)
p heterogeneity	NS	NS	NS	NS

CD: celiac disease; CI: confidence interval; NS: not significant; RR: relative risk; SCC: squamous cell carcinoma.

^aDuodenum, jejunum and ileum.