Table 3.

CD-related relative risks for lymphoma and gastrointestinal carcinoma, by time since CD diagnosis.

	T-cell lymphoma	Small bowel adenocarcinomaa	Esophageal SCC	Colorectal carcinoma
	RRb (95% CI)	RRb (95% CI)	RRb (95% CI)	RRb (95% CI)
No CD	1.0 (reference)	1.0 (reference)	1.0 (reference)	1.0 (reference)
CD	30.4 (21.9–42.2)	9.7 (6.3–15.1)	3.9 (2.2–6.6)	1.2 (0.9–1.5)
Time since CD diagnosis
<1 year n (cases with CD)	157.7 (92.2–269.6) n = 28	38.0 (17.8–81.0) n = 9	4.9 (1.2–20.6) n = 2	5.1 (3.1–8.3) n = 43
≥ 1 year n (cases with CD)	12.7 (7.6–21.3) n = 16	6.4 (3.7–11.2) n = 13	3.7 (2.1–6.7) n = 12	0.7 (0.5–0.9) n = 50
p heterogeneity	<0.001c	<0.001d	NS	<0.001c

CD: celiac disease; CI: confidence interval; NS: not significant; RR: relative risk; SCC: squamous cell carcinoma.

^aDuodenum, jejunum and ileum.

^bAdjusted for gender and age at case or control diagnosis, based on unconditional logistic regression.

^cp value trend < 0.001.

^dp value trend = 0.10.