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. 2018 Dec 17;18:1262. doi: 10.1186/s12885-018-5190-z

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Point mutations identified in tumour tissue of primary orbital melanoma. a Two cases (patients 4 and 5) harboured a heterozygous mutation in GNAQ (c.A626T, p.Q209L). b A recurrent heterozygous mutation in SF3B1 (c.G1874A, p.R625H) was identified in four patients with favourable prognoses (cases 4, 9, 11, 12). c One patient, case 10, carried a heterozygous change in EIF1AX (c.A11T, p.N4S)