Table 1.

Summary of clinical characteristics of 11 patients with primary orbital melanoma. “RT” denotes fractionated external beam radiotherapy. † indicates a deceased patient

Case no.	Gender	Age at onset (years)	Side	Primary treatment of orbital disease	Orbital progression	Time orbital treatment to orbital recurrence (months)	Systemic progression	Time orbit to systemic disease (months)	Systemic therapy	Survival (months)	Notes
1	F	81	R	Debulking	N	–	Y	0		3†	Too unwell for adjuvant radiotherapy
2	M	40	L	Exenteration	N	–	Y	0		4†	Too unwell for adjuvant radiotherapy
4	F	58	L	Exenteration	Unknown	–	Unknown	–		25	Patient declined adjuvant radiotherapy & active follow up
5	M	45	L	Debulking + RT	Y	6	N	–		37	Exenteration after orbital progression
6	F	84	R	Exenteration + RT	N	–	Y	12	Palliative RT for bone metastases	18†	Conjunctival melanosis
8	M	45	L	Debulking + RT	Y	7	Y	45	Liver resection	91	Nevus of Ota Exenteration after orbital progression
9	F	47	L	Debulking + RT	Y	161	Y	168	Nil active	174†	Conjunctival nevus Late exenteration
10	M	46	R	Debulking +RT	N	–	N	–		26
11	F	43	L	Debulking + RT	N	–	N	–		188	West African
12	F	70	L	Debulking +RT	N	–	N	–		22
13	M	55	R	Debulking + RT	Y	2	Y	5	Immunotherapy	35	Immunotherapy for progressive systemic and orbital disease