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. 2018 Dec 17;16:235. doi: 10.1186/s12957-018-1535-y

Table 2.

Linear regression analysis between clinicopathologic characteristics and normalized SLC7 family gene expression in thyroid cancer patients

Gene Age Tumor size Gender (male) Absence of thyroiditis Absence of ETE AJCC stage (III/IV) BRAF mutation RAS mutation Mortality
SLC7A1 ++
SLC7A2 +++
SLC7A3 ++ + ++ +
SLC7A4 +++ −−−
SLC7A5 +
SLC7A6 −−− +++
SLC7A7 +++
SLC7A8 −− −− + −−
SLC7A9 ++ −−−
SLC7A10
SLC7A11
SLC7A13
SLC7A14

+, positive correlation with P value < .05; ++, positive correlation with P value < .01; +++, positive correlation with P value < .001

−, negative correlation with P value < .05; −, negative correlation with P value < .01; −−, negative correlation with P value < .001