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. 2018 Dec 17;19:38. doi: 10.1186/s12865-018-0280-x

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Proteomic analysis of sera from AS patients. a. Heat map representing the 56 protein candidates targeted by IgG antibodies in AS patient sera with 4-fold or greater expression (P < 0.05) compared with healthy donors. The classification and clustering of different categories of cellular component (b), molecular function (c) and biological process (d) of all identified proteins were analyzed using PANTHER databases