Figure 3. Deletion of Irisin/FNDC5 prevented OVX-induced osteocytic osteolysis at 9 months of age.
Tibia samples from the OVX experiment in Fig. 2 were analyzed to measure lacunae area using backscatter scanning electron microscopy. (A-D) Representative figures. Arrow indicates lacunae. (E) Analyzed lacunae area. Data are represented as mean ± SEM. n = 4–7 animals/group. See also Table S3. *; p<0.05.