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. 2018 Nov 19;115(49):12447–12452. doi: 10.1073/pnas.1810647115

Fig. 2.

Fig. 2.

SIR interactions with WT and H4K16Q arrays are distinct. (A) EMSA of Sir3 titrated onto WT and H4K16Q arrays in the absence or presence of Sir2–4 complex. (B and C) vHW plots of Sir2–4, Sir3, and Sir3 and Sir2–4 complex added to WT and H4K16Q arrays. (D) 2DSA/GA-MC modeling results of the sedimentation data in B and C. Numbers in brackets represent expected molecular masses. Numbers in parentheses are 95% confidence intervals. Stoichiometries upon addition of Sir3 and Sir2–4 are speculative.