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. 2017 Apr 12;49(5):447–455. doi: 10.1055/s-0043-104527

Table 2. General characteristics of the pediatric group and the control group.

Pediatric group (n = 72) Control group (n = 1063) P value
Mean age ± SD at onset of chronic pancreatitis, years 9.9 ± 4.8 37.0 ± 14.1 < 0.001
Mean age ± SD at diagnosis of chronic pancreatitis, years 14.0 ± 3.5 42.8 ± 13.0 < 0.001
Mean age ± SD at which stone(s) were identified, years 14.1 ± 3.5 43.0 ± 12.8 < 0.001
Male sex, n (%) 41 (56.9 %) 774 (72.8 %) 0.004
Alcohol, n (%) 1 (1.4 %) 521 (49.0 %) < 0.001
Smoking, n (%) 1 (1.4 %) 558 (52.5 %) < 0.001
Etiology, n (%)  < 0.001

  • Alcoholic chronic pancreatitis

 0 280 (26.3 %)

  • Idiopathic chronic pancreatitis 1

69 (95.8 %) 738 (69.4 %)

  • Others 2

3 (4.2 %) 45 (4.2 %)
Symptoms of chronic pancreatitis onset, n (%) 0.001

  • Abdominal pain

 68 (94.4 %) 810 (76.2 %)

  • Diabetes mellitus/steatorrhea

 4 (5.6 %) 192 (18.1 %)

  • Others

 0 61 (5.7 %)
Type of abdominal pain, n (%) 0.16

  • Recurrent acute pancreatitis

 16 (22.2 %) 361 (34.0 %)

  • Recurrent abdominal pain without significantly increased serum amylase

 21 (29.2 %) 293 (27.6 %)

  • Recurrent acute pancreatitis and abdominal pain without significantly increased serum amylase

 29 (40.3 %) 319 (30.0 %)

  • Chronic pancreatic pain

 6 (8.3 %) 90 (8.5 %)
Severe acute pancreatitis, n (%) 1 (1.4 %) 30 (2.8 %) 0.41
Diabetes mellitus, n (%) 4 (5.6 %) 317 (29.8 %) < 0.001
Steatorrhea, n (%) 4 (5.6 %) 276 (26.0 %) < 0.001
Common bile duct stenosis, n (%) 0 95 (8.9 %) 0.008
Pancreatic pseudocyst, n (%) 11 (15.3 %) 145 (13.6 %) 0.70
Location of stone(s), n (%) 0.45

  • Head

 48 (66.7 %) 760 (71.5 %)

  • Body/tail

 1 (1.4 %) 28 (2.6 %)

  • Head and at least another location

 23 (31.9 %) 275 (25.9 %)

SD, standard deviation.

1

Whether pancreatic divisum and anomalous pancreaticobiliary junction are etiologies of chronic pancreatitis is disputable. Herein, these features are included under idiopathic chronic pancreatitis.

2

Includes hereditary chronic pancreatitis, pancreatic trauma, pancreatic anatomical abnormality, and hyperlipidemia. Among the pediatric patients, there was one case of hereditary chronic pancreatitis and two of pancreatic trauma. In the control group, there were 17 cases of hereditary pancreatitis, 24 of pancreatic anatomical abnormalities, two of pancreatic trauma, and two of hyperlipidemia.