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. 2018 Dec 14;10:6971–6984. doi: 10.2147/CMAR.S182852

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© 2018 Wang et al. This work is published and licensed by Dove Medical Press Limited

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Overexpression of FOXM1 significantly reverses the inhibition of proliferation caused by CENPU knockdown.

Notes: (A) The mRNA expression level of FOXM1 was significantly upregulated 48 hours after FOXM1 plasmid transfection. (B) Western blotting showed that the protein expression of FOXM1 was significantly upregulated 48 hours after FOXM1 plasmid transfection. (C) Cell proliferation rates were determined by EdU assays in SPC-A1 and A549 cells between NC, siCENPU, FOXM1, and siCENPU plus FOXM1 group. ***P<0.001; **P<0.01; and *P<0.05 (mean ± SEM).

Abbreviations: CENPU, centromere protein U; EdU, 5-ethynyl-2’-deoxyuridine; FOXM1, Forkhead box protein M1; NC, negative control; SEM, standard error of the mean; siCENPU, CENPU siRNA.