Table 2.
Hematological values of male C57BL/6 mice 14 days after receiving a single dose of vehicle or mangosteen fruit extract (100 mg/kg)
| Control (Vehicle) | Mangosteen Fruit Extract (100 mg/kg) | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | 2 | 3 | 4 | Average | 1 | 2 | 3 | 4 | Average | |
|
|
|
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| WBC (x 103/μL) | 7.6 | 10.4 | 8.2 | 7.0 | 8.3 ± 1.5 | 8.9 | 7.5 | 5.2 | 7.8 | 7.3 ± 1.6 |
| RBC (x 106/μL) | 10 | 9.38 | 10 | 10.3 | 9.9 ± 0.4 | 10.6 | 9.6 | 9.4 | 9.5 | 9.8 ± 0.6 |
| HGB (g/dL) | 14.5 | 13.5 | 14.2 | 15.1 | 14.3 ± 0.7 | 15.6 | 14.1 | 14 | 14 | 14.4 ± 0.8 |
| HCT (%) | 48.3 | 45.3 | 47 | 48.8 | 47.4 ± 1.6 | 56.5 | 51.8 | 50.4 | 50.5 | 52.3 ± 2.9 |
| MCV (fL) | 48.3 | 48.3 | 47 | 47.2 | 47.7 ± 16.9 | 53.3 | 53.9 | 53.6 | 53.3 | 53.5 ± 0.3 |
| PLT (x 103/μL) | 1230 | 1064 | 1071 | 239 | 901 ± 448 | 992 | 1392 | 616 | 1231 | 1058 ± 337 |
| MPV (fL) | 6.4 | 7 | 7 | 7.7 | 7.0 ± 0.5 | 4.7 | 6 | 5.1 | 6.1 | 5.5 ± 0.7 |
| RDW (%) | 12.6 | 13.3 | 12.4 | 11.6 | 12.5 ± 0.7 | 11.6 | 12.7 | 12.2 | 11.8 | 12.1 ± 0.5 |
| Retic (%) | 3.3 | 5.4 | 3.1 | 3.4 | 3.8 ± 1.1 | 4.3 | 3.9 | 3.3 | 4.6 | 4.0 ± 0.6 |
| Retic (x 109/μL) | 328 | 510 | 308 | 308 | 363.3 ± 98 | 460 | 374 | 313 | 432 | 395 ± 65 |
| Neutrophil (%) | 9.5 | 13.8 | 6.6 | 14.4 | 11.1 ± 3.7 | 6.8 | 18.1 | 4.6 | 6.3 | 9.5 ± 6.2 |
| Lymphocyte (%) | 86.4 | 79.5 | 88.5 | 75.1 | 82.4 ± 6.2 | 86.7 | 74.9 | 85.1 | 88.5 | 83.8 ± 6.1 |
| Monocyte (%) | 0.6 | 0.6 | 1 | 1.5 | 0.9 ± 0.4 | 1.3 | 2 | 4.9 | 1.2 | 2.4 ± 1.7 |
| Eosinophil (%) | 1.9 | 4 | 2.3 | 8 | 4.1 ± 2.8 | 3.4 | 2.6 | 4.3 | 1.9 | 3.1 ± 1.0 |
| Basophil (%) | 0.3 | 0.4 | 0.4 | 0.5 | 0.4 ± 0.1 | 0.5 | 0.6 | 0.5 | 0.7 | 0.6 ± 0.1 |
The values are expressed as mean ± SD. WBC = White Blood Cells; RBC = Red Blood Cells; HGB = hemoglobin; HCT = hematocrit; MCV = Mean Corpuscular Volume; MCH = Mean Corpuscular Hemoglobin; MCHC = Mean Corpuscular Hemoglobin Concentration; MPV = Mean Platelet Volume; RDW = Red Cell Distribution Width; Retic = Reticulocyte Count