Table 2. List of miRNAs regulated by EPA.

Fifteen miRNAs were differentially expressed between HF and HF-EPA diets in B6 mice. Nine and 6 miRNAs were upregulated and downregulated by EPA respectively. HF, high fat; HF-EPA, HF diet supplemented with EPA; RPKM, reads per kilo base per million mapped reads.

miRNA Name	RPKM HF	RPKM HF-EPA	Fold Change	P value
Upregulated miRNA
miRNA-17–3p	3.74	5.33	1.59	0.03
miRNA-129–2-3p	9.75	11.30	1.55	0.01
miRNA-129–5p	8.70	10.27	1.57	0.01
miRNA-129–1-3p	3.32	4.94	1.61	0.01
miRNA-148a-5p	6.56	7.22	0.67	0.02
miRNA-150–5p	14.52	15.26	0.74	0.02
miRNA-181c-3p	3.85	5.33	1.7	0.04
miRNA-2137	12.48	13.27	0.79	0.03
miRNA-455–3p	12.15	13.52	1.38	0.05
Downregulated miRNA
miRNA-125b-1–3p	7.66	6.44	−1.22	0.03
miRNA-199a-3p	10.3	9	−1.03	0.03
miRNA-199b-3p	10.3	9	−1.03	0.03
miRNA-3102–3p	7.50	4.26	−3.24	0.03
miRNA-503–3p	4.89	3.32	−1.57	0.00
miRNA-674–5p	7.22	5.52	−1.7	0.02