Table 1.
Participant Characteristics, Pilot versus Full Strong Heart Family Study Cohort
| Pilot (N=59) | Full Cohort (N=1577)a | |
|---|---|---|
| Age (years), median (IQR) | 35.3 (26.4, 46.3) | 35.3 (23.6, 46.3) |
| Sex | ||
| Male, n (%) | 28 (47.5) | 654 (41.6) |
| Female, n (%) | 31 (52.5) | 923 (58.4) |
| Smoking | ||
| Never, n (%) | 25 (42.4) | 647 (41.1) |
| Ever, n (%) | 13 (22.0) | 325 (20.6) |
| Current, n (%) | 21 (35.6) | 604 (38.3) |
| Alcohol Intake | ||
| Never, n (%) | 8 (13.6) | 173 (11.0) |
| Ever, n (%) | 15 (25.4) | 406 (25.8) |
| Current, n (%) | 36 (61.0) | 997 (63.3) |
| BMI (kg/m2) | 31.6 (25.9, 38.0) | 29.8 (25.5, 35.0) |
| Vitamin B6 intake (mg) | 1.60 (1.05, 2.65) | 1.70 (1.10, 2.60) |
| <RDAb, n (%) | 21 (35.6) | 545 (34.6) |
| ≥RDAb, n (%) | 38 (64.4) | 1032 (65.4) |
| Vitamin B2 intake (mg) | 1.60 (1.00, 2.30) | 1.70 (1.10, 2.70) |
| <RDAc, n (%) | 19 (32.2) | 358 (22.7) |
| ≥RDAc, n (%) | 40 (67.8) | 1219 (77.3) |
| Folate intake (μg) | 348 (226, 518) | 360 (234, 559) |
| <RDAd, n (%) | 37 (62.7) | 890 (56.4) |
| ≥RDAd, n (%) | 22 (37.3) | 687 (43.6) |
| Plasma Folate (nmol/L) | 51.3 (40.2, 63.9) | --- |
| Plasma Homocysteine (μmol/L) | 7.53 (5.85, 8.98) | --- |
| ΣAs (μg/g) | 3.66 (2.64, 8.27) | 4.59 (3.02, 7.49) |
| iAs% | 10.7 (7.29, 16.4) | 10.0 (6.94, 14.1) |
| MMA% | 15.3 (11.3, 19.9) | 14.5 (11.1, 18.2) |
| DMA% | 72.9 (65.9, 78.8) | 74.6 (67.8, 80.8) |
| HOMA2-IR | 1.44 (1.06, 2.62) | 1.44 (0.97, 1.44) |
| Fasting Plasma Glucose (mg/dL) | 93.0 (89.0, 101.5) | 93.0 (87.0, 100.0) |
| Waist Circumference (cm) | 105.0 (91.5, 117.5) | 99.0 (88.0, 111.0) |
Abbreviations: RDA (recommended dietary allowance); ΣAs (sum of inorganic arsenic and its methylated metabolites); iAs (inorganic arsenic); MMA (monomethylarsonic acid);DMA (dimethylarsinic acid)
a
Excluding participants with missing data on variables in table
b
RDA for B6: Males (≤50 years=1.3 mg; >50=1.7 mg); Females (14–18 years=1.2 mg; 19–50 years=1.3 mg; >50 years=1.5 mg)
c
RDA for B2: Males (≥14 years =1.3 mg); Females (14–18 years=1.0 mg; >18 years=1.1 mg)
d
RDA for folate: Males and Females ≥14 years=400 μg