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. 2018 Jul 1;37(3):320–327. doi: 10.1515/jomb-2017-0060

Table I.

Patients characteristics.

(No=68 patients) Age Years
Average 6.5
Median 5.2
Range 0.9–17.6
Gender %
Male 38 56
Female 30 44
Immunophenotype
B lineage 58 85
T lineage 10 15
Molecular genetics
Negative 47 69
BCR/ABL 3 4
MLL/AF4 2 3
TEL/AML1 14 21
E2A/PBX1 2 3
Applied protocol
ALL IC BFM 2002 39 57
ALL IC BFM 2009 29 43
Prednisolone response
Good response 61 90
Poor response 7 10
Day 33 BM
M1 67 98
M2 0 0
M3 1 2
Risk group
Standard risk 11 16
Intermediate risk 47 69
High risk 10 15
Outcome
CR 59 87
Relapse 5 7
Death due to relapse 4 6

Good prednisolone response: <1000 leukoblasts per mm3, poor prednisolone response: >1000 leukoblasts per mm3, BM: bone marrow, M1:<5% leukoblasts in BM, M2: ≥5% <25% leukoblasts, M3: ≥25% leukoblasts, CR: complete remission