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. 2019 Jan;26(1):24–30. doi: 10.1101/lm.048264.118

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Published by Cold Spring Harbor Laboratory Press

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Figure 3. — Effects of lOFC and dmPFC inactivation on late three-choice reversal performance. (A) Experimental timeline for post-reversal criterion inactivation. (B) lOFC inactivation did not significantly affect the percentage of S^prior (left panel; corrected t₍₁₆₎ = 2.03, P = 0.1160), S^new (middle panel; corrected t₍₁₆₎ = 2.39, P = 0.0856), or S^never (right panel; corrected t₍₁₆₎ = 1.99, P = 0.1160) choices. (C) The average length of S^prior strings was increased by lOFC inactivation (left panel; t₍₁₆₎ = 2.61, P = 0.0190), while the average S^new string length was diminished by lOFC inactivation (middle panel; t₍₁₆₎ = 2.45, P = 0.0261). In contrast, S^never string length was not altered by lOFC inactivation (right panel; t₍₁₄₎ = 0.98, P = 0.3450). (D,E) Inactivation of the dmPFC at late reversal did not significantly affect any measure (all t-values <1.5, all P-values > 0.15). n = 9–10 per group. Data are means ± SEM. (*) P < 0.05.