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. 2019 Jan;26(1):1–8. doi: 10.1101/lm.048025.118

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© 2019 Barker et al.; Published by Cold Spring Harbor Laboratory Press

This article is distributed exclusively by Cold Spring Harbor Laboratory Press for the first 12 months after the full-issue publication date (see http://learnmem.cshlp.org/site/misc/terms.xhtml). After 12 months, it is available under a Creative Commons License (Attribution-NonCommercial 4.0 International), as described at http://creativecommons.org/licenses/by-nc/4.0/.

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Figure 3. — Effects of ventral hippocampus inhibition may be selective to contingency degradation. (A) To determine if inhibition of the ventral hippocampus prevented the use of cues to guide behavior, a subset of animals expressing the Gi-DREADD in the ventral hippocampus underwent Pavlovian conditioning in which a cue predicted sucrose delivery. Administration of CNO did impact the expression of cue-guided consummatory behavior. (B) Inhibition of the ventral hippocampus did not impact the acquisition of extinction of sucrose seeking.