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. Author manuscript; available in PMC: 2018 Dec 18.
Published in final edited form as: Pediatrics. 2018 Aug;142(2):e20181410. doi: 10.1542/peds.2018-1410

TABLE 1.

Summary of Food-Related Uses and Health Concerns for the Compounds Discussed in This Report

Category Chemical Food-Related Use Selected Health Concerns
Indirect food additives Bisphenols Polycarbonate plastic containers
Polymeric, epoxy resins in food and beverage cans
Endocrine disruption1118
Obesogenic activity,1922 neurodevelopmental disruption2326
Phthalates Clear plastic food wrap
Plastic tubing, storage containers used in industrial food production
Multiple uses in food manufacturing equipment
Endocrine disruption6,2729
Obesogenic activity3032
Oxidative stress,33,34 cardiotoxicity35,36
Perfluoroalkyl chemicals (PFCs) Grease-proof paper and paperboard Immunosupression,37,38 endocrine disruption,3941 obesogenic activity,42 decreased birth wt43
Perchlorate Food packaging Thyroid hormone disruption4446
Direct food additives Nitrates and nitrites Direct additive as preservative and color enhancer, especially to meats Carcinogenicity,10,47,48 thyroid hormone disruption49,50