TABLE 4.
DNA viruses produce PAMPs and DAMPs during infection that activate inflammasomes and other sensors
| Virus (type of genome) | Inflammasome sensor(s) [activator(s)] [reference(s)] |
|---|---|
| Adenovirus (dsDNA) | NLRP3 (cathepsin B, ROS) (208, 210, 212, 213) |
| Bovine herpesvirus 1 (dsDNA) | IFI16 (viral DNA) (428), NLRP3 (unknown activator) (428) |
| Epstein-Barr virus (dsDNA) | AIM2 (viral DNA) (200, 204), IFI16 (viral DNA) (429) |
| Hepatitis B virus (circular, partially dsDNA) | AIM2 (viral DNA) (198, 203, 430, 431) |
| Herpes simplex virus (dsDNA) | NLRP3 (ROS) (201, 205–207), IFI16 (viral DNA) (205, 215) |
| Human bocavirus (ssDNA) | NLRP3 (viral noncoding RNA) (432) |
| Human cytomegalovirus (dsDNA) | AIM2 (viral DNA) (193) |
| Human papillomavirus 16 (dsDNA) | AIM2 (viral DNA) (199) |
| Kaposi's sarcoma-associated herpesvirus (dsDNA) | IFI16 (viral DNA) (433, 434) |
| Modified vaccinia virus Ankara (dsDNA) | AIM2 (viral DNA) (201), NLRP3 (unknown activator) (168, 209) |
| Mouse cytomegalovirus (dsDNA) | AIM2 (viral DNA) (162, 164) |
| Vaccinia virus (dsDNA) | AIM2 (viral DNA) (31, 164) |
| Varicella-zoster virus (dsDNA) | NLRP3 (unknown activator) (211) |